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PAUL THOMPSON, Ph.D.
Assistant Professor of Chemistry and Biochemistry
DEGREES
B.Sc., 1994, McMaster University
Ph. D., 2000, McMaster University
RESEARCH INTERESTS
Our research group is interested in the rational design of anti-cancer chemotherapeutics, focusing our studies on enzymes involved in regulating the structure of chromatin (Figure 1). In response to stimuli, nucleosomal histones are variably phosphorylated, ubiquitinated, methylated, and/or acetylated and these covalent marks are thought to help specify regions of chromatin that are transcriptionally competent (open) or transcriptionally repressive (closed). Specifically, we are interested in understanding the molecular mechanisms of a number of histone acetyltransferases, methyltransferases, and arginine deiminases.
CONTACT INFORMATION
University of South Carolina | Dept. of Chemistry and Biochemistry| 631 Sumter StreetColumbia, SC 29208 | E-mail
Office: GSRC 407 803-777-6414 | Lab: GSRC 406 803-777-2334 | Lab 2: GSRC 405 |
Fax: 803-777-9521
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