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ROBERT L. PRICE , Ph.D.
Professor, USC School of Medicine, Cell and Developmental Biology and Anatomy
Director, CCCR Histology and Imaging Core
DEGREES
B.S., 1976, Lake Superior State College. Cum Laude
M.S., 1979, Southern Illinois University
Ph.D., 1983, Southern Illinois University
RESEARCH INTERESTS
Dr. Price's research interests include the role of growth factors in heart development and the effects of mechanical load on heart development and disease processes. His primary interests involve the roles of growth factors and mechanical forces on the development and function of myofibrils in cardiac myocytes. His recent publications have demonstrated the importance of these factors in the normal development of the contractile apparatus of the heart.
Dr. Price's laboratory uses a variety of research techniques including RT-PCR, biochemical analysis of proteins, and the immuno-localization of proteins by confocal scanning laser and electron microscopy to determine myofibril form and function. Research models include cell and whole embryo culture as well as in vivo analyses utilizing embryonic, fetal, neonatal and adult animals.
RECOGNITION
Honors and Extramural Service:
1986 Microscopy Society of America Diatome Award
1987-2005 Member, Electron Microscopy Society of America Education Committee
2000-2001 Microscopy and Microanalysis 2001, Long Beach, CA Program Chair
2003, 2005 Research Advancement Award, USC School of Medicine
2003 Southeastern Microscopy Society Distinguished Scientist Award
2004-2005 Microscopy and Microanalysis 2005, Honolulu, HA Program Chair
2002, 2004-2005 NIH Shared Instrumentation Study Section for Confocal Microscopy
2005-Present Editor, Biological Applications, Microscopy and Microanalysis, The Journal of the Microscopy Society of America
2006 American Heart Association Mid-Atlantic Affiliate Study Section for Cell Signaling
Presentations:
Platelet Derived Growth Factor in Heart Development. 39th American Society for Cell Biology Annual Meeting. Washington, DC. 1999. (With T.E. Thielen, E. Goldsmith, T.K. Borg and L. Terracio).
Angiotensin II in Heart Development. 39th American Society for Cell Biology Annual meeting. Washington, SC. 1999. (With T.E. Thielen, T.K. Borg and L. Terracio).
In vivo characterization of cardiac tissue defects associated with PDGFRa gene deletion in the patch mouse. 57th Annual meeting of the Microscopy Society of America, Portland OR. 1999. (With T.E. Thielen, T.K. Borg and L. Terracio).
Microscopy as a Tool in Understanding the Role of Growth Factors in Cardiac Development. 57th Annual meeting of the Microscopy Society of America, Portland OR. 1999. Invited Speaker.
The Role of Platelet Derived Growth Factor (PDGF) in Cardiac Development. 1999 Weinstein Cardiovascular Development Conference. Tucson, AZ. (With T. E. Thielen, D.G. Simpson, T.K. Borg and L. Terracio).
Angiotensin and PDGF in cardiac development. Poster at Vanderbilt Weinstein meeting. 1999. (With T.E. Thielen, T.K. Borg and L. Terracio).
Aortic Stenosis in Mice with LV Hypertrophy. Poster presented by B. Lorell at 1999 American Heart Association meeting. (With B. Lorell, R.L. Price, E.O. Weinberg, T.K. Borg and B.O. Ding).
Growth factors in Cardiac Development. 1998. Invited presentation to the Cardiac Residents Program. Richland Memorial Hospital. Columbia, SC.
Temporal and spatial expression patterns of PDGF receptors in embryological rat heart as detected through confocal scanning laser microscopy. Poster at the 1998 Atlanta Microscopy Society of America meeting. (With T.E. Thielen, T.K. Borg and L. Terracio).
The role of PDGF in cardiac development. 1998. Invited presentation to the South Carolina Statewide Research Symposium.
The effects of angiotensin II and PDGF BB on cardiac development in the early rat embryo. Invited presentation at The Department of Cell Biology and Anagomy and the Cardiovascular Developmental Biology Center, Medical University of South Carolina. 1998.
The effects of PDGF BB on embryonic cardiac development. Poster presented at the 1998 Weinstein Developmental Cardiology meeting. (With T.E. Thielen, D.G. Simpson, W. Carver, T.K. Borg and L. Terracio).
Potential role of angiotensin II in hearly heart development. Keystone Symposia on "The Molecular Biology of the Cardiovascular System". 1997. Keystone, CO (Presented by W. Carver with D.G. Simpson, T.K. Borg and L. Terracio).
The effects of angiotensin II and PDGF on early cardiac development in the rat. Invited presentation at The Children's Hospital Research Foundation Division of Molecular Cardiology. 1997.
The effect of angiotensin II on early embryonic heart development. Invited presentation at the Fall 1997 Appalacian Region Microscopy Society Meeting.
Practical considerations and applications of digital imaging in a core microscopy facility. Invited presentation at 54th Annual meeting of the Microscopy Society of America. 1996
Myofibrillogenesis and myofiber pattern in normal and angiotensin induced cardiac inversion in developing rat heart. Poster presented at 53rd Annual meeting of the Microscopy Society of America, 8/95 (with L. Fu, D.G. Simpson, L. Terracio, and T.K. Borg)
Some aspects of in vivo and in vitro cardiac myocyte development. Invited presentation at 1994 Appalachian Region Electron Microscopy Meeting.
Fluorescent microspheres as probes of microvascular protein permeability. Poster presented at 1993 FASEB meeting. (Presented by M.B. Wolf with R.K. Jyring)
Collagen ratios in exercise-trained and pressure-overloaded rat hearts. Poster presented at 51st Annual meeting of the Electron Microscopy Society of America, 8/93 (with M.L. Burgess, F.L. Abel, G.P. Jones, L. Terracio, T.K. Borg)
Confocal and electron microscopy of cultured cardiac myocytes. Poster presented at 51st Annual meeting of the Electron Microscopy Society of America, 8/93 (with D.G.Simpson, M. Terracio, L. Terracio, and T.K. Borg)
Morphogenesis of murine leukemia viruses: Actin involvement and new surface features seen by HVEM. Poster presented at 1993 FASEB meeting. (Presented by R.B. Luftig with J. Coward and D.L. Lupo).
Localization of aminomalonic acid (AMA) epitope in granuloma foam cells. Poster presented at 1991 FASEB meeting. (Presentation by S.D. Fowler with T. Sullivan, P.D. Gasque-Carter, W.J. Sasiela, S.D. Copley, E. Frank, T.H. Koch, R. Hunsaker, S. Nehlsen-Cannarella, and W. M. Kirsch).
Expression of laminin and beta-1 integrin in embryonic, neonatal, and adult rat heart. Paper presented at 49th Annual meeting of the Electron Microscopy Society of America, 8/91 (with T.K. Borg, L. Terracio, and M. Nakagawa).
Microtubule number increases locally within regions of axonal compression. Poster presented at 47th annual meeting of the Electron Microscopy Society of America, 8/89 (with R.J. Lasek and M.J. Katz).
Neurofilaments pack differently in different parts of the same axon. Poster presented at the 46th Annual meeting of the Electron Microscopy Society of America, 8/88. (With R.J. Lasek and M.J. Katz).
Different neurofilament densities show identical random distributions in side-by-side axons. Poster presented at the 45th annual Meeting of the Electron Microscopy Society of America, 8/87. (With P. Paggi, R.J. Lasek, and M.J. Katz).
The density of neurofilaments differs in the somatic motor and parasympathetic oculomotor axons of chickens. Poster presented at the 44th Annual Meeting of the Electron Microscopy Society of America, 8/86. (With P. Paggi and R.J. Lasek).
Transport rate and organization of neurofilaments differ in somatic motor and parasympathetic axons. Poster presented at the Neurosciences Meetings, 12/86. (With P. Paggi and R.J. (Lasek).
Biology and Ultrastructure of Pleistophora campostomae n. sp. (Protozoa: Microsporida) from the stoneroller Campostoma anomalum. Invited presentation at Stephen F. Austin State University, Nacogdoches, TX. 3/83.
Ultrastructural study on the development of Pleistophora campostomae (Protozoa: Microsporida) from the stoneroller, Campostoma anomalum. Paper presented at the Central States Electron Microscopy Society, 5/83.
Light and electron microscopy of Pleistophora campostomae (Protozoa: Pleistophoridae) from the stoneroller, Campostoma anomalum. Paper presented at the annual Midwest Conference of Parasitologists, 6/83.
Use of LR White embedding medium in routine transmission electron microscopy. Paper presented at the 41st Annual Meeting of the Electron Microscopy Society of America, 8/83. (With J.A. Murphy).
Use of Methacrylate embedding media for sectioning of Acanthocephala. Poster presented at the Annual Midwest Conference of Parasitologists, 6/82.
Incidence of Pleistophora cepedianae (Microsporidia) in gizzard shad (Dorosoma cepedianum) of Carlyle Lake, Illinois. Paper presented at the Illinois Chapter of the American Fisheries Society, 2/80
Preliminary investigation on the ultrastructure of the mature Pleistophora cepedianae (Microsporida: Nosematidae) spores. Poster presented at the Annual Midwest Conference of Parasitologists, 6/80
Incidence of Pleistophora cepedianae (Microsporidia) in gizzard shad (Dorosoma cepedianum) of Carlyle Lake, Illinois. Paper presented at the Annual Midwest Conference of Parasitologists, 6/80
CONTACT INFORMATION
Instrumentation Resource Facility
University of South Carolina
School of Medicine
Columbia, SC 29208
E-mail
Office: 803 . 733 . 3393 | Fax: 803 . 733 . 1533
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