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DAN A. DIXON, PhD Lab

PUBLICATIONS (2000 to present)
Ying L, Marino J, Hussain SP, Khan MA, Trivers GE, Dixon DA, Harris CC, Hofseth LJ. Chronic Inflammation Promotes Retinoblastoma Protein Hyperphosphorylation and E2F1 Activation. (2005) Cancer Res. in press.

Peng G, Wargovich MJ, Dixon DA. Anti-proliferative effects of green tea polyphenol EGCG on Ha-Ras-induced transformation of intestinal epithelial cells. Cancer Lett. 2005 Sep 9

Weyrich AS, Denis MM, Kuhlmann-Eyre JR, Spencer ED, Dixon DA, Marathe GK, McIntyre TM, Zimmerman GA, Prescott SM. Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates. Circulation. 2005 Feb 8;111(5):633-42.

Weyrich AS, Lindemann S, Tolley ND, Kraiss LW, Dixon DA, Mahoney TM, Prescott SP, McIntyre TM, Zimmerman GA. Change in protein phenotype without a nucleus: translational control in platelets. Semin Thromb Hemost. 2004 Aug;30(4):491-8.

Li JQ, Wu F, Masaki T, Kubo A, Fujita J, Dixon DA, Beauchamp RD, Ishida T, Kuriyama S, Imaida K. Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors. Int J Oncol. 2004 Jul;25(1):87-95.

Dixon DA. Dysregulated post-transcriptional control of COX-2 gene expression in cancer. Curr Pharm Des. 2004;10(6):635-46.

Parker MA, Deane NG, Thompson EA, Whitehead RH, Mithani SK, Washington MK, Datta PK, Dixon DA, Beauchamp, RD. (2003) Over-expression of cyclin D1 regulates Cdk4 protein synthesis. Cell Prolif. 36: 347-360.

Dixon DA, Balch GC, Kedersha N, Anderson P, Zimmerman GA, Beauchamp RD, Prescott SM. Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1. J Exp Med. 2003 Aug 4;198(3):475-81.

Subbaramaiah K, Marmo TP, Dixon DA, Dannenberg AJ. Regulation of cyclooxgenase-2 mRNA stability by taxanes: evidence for involvement of p38, MAPKAPK-2, and HuR. J Biol Chem. 2003 Sep 26;278(39):37637-47

Dixon DA. Regulation of COX-2 expression in human cancers. Prog Exp Tumor Res. 2003;37:52-71.

Boutaud O, Dixon DA, Oates JA, Sawaoka H. Tristetraprolin binds to the COX-2 mRNA 3' untranslated region in cancer cells. Adv Exp Med Biol. 2003;525:157-60.

Sawaoka H, Dixon DA, Oates JA, Boutaud O. Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding site. J Biol Chem. 2003 Apr 18;278(16):13928-35.

Kraiss LW, Alto NM, Dixon DA, McIntyre TM, Weyrich AS, Zimmerman GA. Fluid flow regulates E-selectin protein levels in human endothelial cells by inhibiting translation. J Vasc Surg. 2003 Jan;37(1):161-8. Subbaramaiah, K., Marmo, T.P., Dixon, D.A. , and Dannenberg, A.J. Regulation of Cyclooxygenase-2 mRNA stability by Taxanes. Evidence for Involvement of p38, MAPKAP-K2 and HuR. J. Biol. Chem. (2003) 278: 37637-37647.

Zimmerman GA, Dixon DA, McIntyre TM, Prescott SM and Weyrich AS. Molecular Mechanisms of Juxtacrine Signaling in Microvascular Responses and Inflammation. Molecular Mechanisms of Microvascular Disorders. eds. Schmid-Schoenbein, GW, Granger, N.D. Springer Verlag pp.203-217 (2003).

Dixon DA, Tolley ND, Zimmerman GA A Convenient and Rapid Ribonuclease Protection Assay for Studies of Primary Cells. 2001 BioTechniques 31:992-993.

Dixon DA, Tolley ND, King PH, Nabors LB, McIntyre, TM, Zimmerman, GA, Prescott, SM. Altered Expression of the mRNA Stability Factor HuR Promotes Cyclooxygenase-2 Expression in Colon Cancer Cells. J. Clin. Invest. 2001 108:1657-1665.

Lindemann S, Tolley ND, Dixon DA, McIntyre TM, Prescott SM, Zimmerman GA, Weyrich AS. Activated Platelets Mediate Inflammatory Signaling by Regulated Interleukin-1 Synthesis. J. Cell. Biol. 2001 154: 485-490.

Mahoney, T.S., Weyrich, A.S., Dixon, D.A. , McIntyre, T.M., Prescott, S.M., and Zimmerman, G.A. Cell Adhesion Regulates Gene Expression at Translational Checkpoints in Human Myeloid Leukocytes. Proc. Natl. Acad. Sci., USA (2001) 98:10284-10289.

Dixon, D.A. , Kaplan, C.D., McIntyre, T.M., Zimmerman, G.A., and Prescott, S.M. Post-Transcriptional Control of Cyclooxygenase-2 Gene Expression: Role of the AU-Rich 3'Untranslated Region. J. Biol. Chem. (2000) 275:11750-11757.

Kraiss LW, Weyrich AS, Alto NM, Dixon DA, Ennis TM, Modur V, McIntyre TM, Prescott SM, Zimmerman GA Fluid Shear Stress Activates P70/P85 S6 Kinase in Human Endothelial Cells. Amer. J. Phys. 2000 278:1537-1544.

Sheng, H, Shao, J, Dixon, DA, Williams, CS, Prescott, SM, DuBois, RN, and Beauchamp, RD. TGF-1 Enhances Ras-induced Expression of Cyclooxygenase-2 in Intestinal Epithelial Cells via Stabilization of mRNA. J. Biol. Chem. 2000 275:6628-6635.

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