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MARIA MARJORETTE O. (Marj) PENA, Ph.D.
Lab

LAB PERSONNEL
Marj Peņa, Ph.D. - Assistant Professor, USC
PUBLICATIONS
Baltgalvis, K.A., Berger, F.G., Pena, M.M.O., Davis, J.M., Muga, S.J., and Carson, J.A. 2007. Interleukin-6 and Cachexia in ApcMin/+ Mice. Am J Physiology: Integrative and Regulatory. In press.
Peña, M.M.O., Xing, Y., Koli, S., and Berger, F.G.B. 2006. Role of N-terminal residues in the ubiquitin-independent degradation of human thymidylate synthase. Biochem. J. Nov. 1 EPub ahead of print. 394:355-363.
You, S., Ohmori, M., Peña, M.M.O., Nassri, B., Quiton, J., Al-Assad, Z.A., Liu, L., Wood, P., Berger, S.H., Liu, Z., Wyatt, M., Price, R.L., Berger, F.G., and Hrushesky, W.J.M. 2006. Developmental Abnormalities in Multiple Proliferative Tissues of ApcMin/+ mice. Int J Exp Pathol.87:227-38.
Mehl, K.A., Davis, J.M., Clements, J.M., Berger, F.G., Peña, M.M.O., and Carson, J.A. 2005. Decreased intestinal polyp multiplicity is related to exercise mode and gender in ApcMin/+ mice. J. Appl. Physiology. 98:2219-2225.
Nivens, M.C., Felder, T., Galloway, A.H., Peña, M.M.O., Pouliot, J.J. and Spencer, H.T. 2004. Engineered resistance to camptothecin and antifolates by retroviral coexpression of tyrosyl DNA phospodiesterase-I and thymidylate synthase. Cancer Chemother Pharmacol. 53:107-115.
Forsthoefel, A.M., Peña, M.M.O., Xing, Y.Y., Rafique, Z and Berger, F.G. 2004. Structural Determinants for the Intracellular Degradation of Human Thymidylate Synthase. Biochemistry. 43:1972-1979.
Lee, Jaekwon, Peña, M.M.O., Yasuhiro Nose, and Dennis J. Thiele. 2002 Biochemical characterization of the human copper transporter Ctr1. J. Biol. Chem. 277:4380-4387.
Peña, M.M.O., Puig, S., and Thiele, D.J. 2000. Characterization of the Saccharomyces cerevisiae high affinity copper transporter, Ctr3. J. Biol. Chem. 275:33244-33251.
Labbe, S. L., Peña, M.M.O., Fernandes, A.R., Thiele, D.J. 1999. A copper-sensing transcription factor regulates iron uptake genes in Schizosaccharomyces pombe. J. Biol. Chem. 274:36252-36260.
Peña, M.M.O., Lee, J. and Thiele, D.J. 1999. A delicate balance: homeostatic control of copper uptake and distribution. Journal of Nutrition. 129:1251-1260.
Peña, M.M.O., Koch, K.A., Thiele, D.J. 1998. Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:2514-2523.
Zhu, Z., Labbe, S., Peña a, M.M.O. and Thiele, D. J. 1998. Copper differentially regulates the activity and degradation of yeast mac1 transcription factor. J. Biol. Chem. 273:1277-1280.
Koch, K.A., Peña, M.M.O., and Thiele, D. J. 1997. Copper-binding motifs in catalysis, transport, detoxifications, and signaling. Chem. & Biol. 4:549-560.
Peña, M.M.O. and Bullerjahn, G.S. 1995. The DpsA protein of Synechococcus sp. strain PCC7942 is a DNA-binding hemoprotein: linkage of the Dps and bacterioferritin protein families. J. Biol. Chem. 270:22478-22482.
Peña, M.M.O., Burkhart, W. and Bullerjahn, G.S. 1995. Purification and characterization of a Synechococcus sp. StrainPCCC7942 polypeptide structurally similar to the stress-induced Dps/PexB protein of Escherichia coli. Arch. Microbiol. 163:337-344.
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