Pathology Core

Director: William (Bill) Hrushesky, MD

WJB Dorn Veterans Affairs Medical Center (151)
6439 Garners Ferry Road
Columbia, SC 29209

Pathology Core Description

...of murine or human tissue, benign or neoplastic. This is a written and/or verbal description of the anatomy and histology of normal tissues and a professional pathologic assessment of any visible pathologic change within H and E sections from tissues which differ in some way from those of normal mice. (eg. Genetically, toxic exposure, therapeutic exposure.) Comparisons with control tissues from age and sex matched normal mice are usually essential.

Technical Support

• The development of scoring methods to objectify pathological changes observed and described (as above) or other pathological processes eg. inflammation.
• The scoring of histopathogical changes in modest numbers of tissue samples. These scorings must be done "blindly" by our staff or our staff can teach you how to do this. This requires the concurrent "blinded" scoring of normal tissues.

The preparation of tissue microarrays of areas of pathological interest (up to 400 samples per slide.) for larger scale qualatative HC/image analysis based assessment either in our core, your lab or the imaging core.

Core Support Staff

• Bill Hrushesky, MD, Chief of Pathology Core, Senior Consultant, Oncologist
  Building 6 | 803.647.5654 | E-mail
• Patricia Wood, MD, PhD, Chief of Oncology, Senior Consultant, Oncology
• Ziad Al-Assaad, MD, Chief, Department of Pathology, VA Medical Center, Senior Pathology Consultant
• Shaojin You (Mark), MD, PhD, Research Pathologist, Core Manager
  Building 9, Room 209/206 | 803.776.4000, ext. 6656 | E-mail
• Glenda Clement, Senior Histologist